Effectiveness of Potassium Oxalate mouthrinse in treating dentinal hypersensitivity
Main Article Content
Abstract
Background: Dentinal hypersensitivity is a prevalent oral condition characterised by a short, sharp pain in response to chemical, thermal, tactile, or osmotic stimuli. It can be treated with the in-office application of potassium oxalate (KO). This study assesses KO mouthrinse for home use.
Aim: To assess the efficacy of Vantej® mouthrinse, containing potassium oxalate (KO), in reducing dentinal hypersensitivity when used in combination with regular brushing for three months.
Materials and methods: In this double-blind, parallel group-controlled study, participants with dentinal hypersensitivity were randomly assigned to Group 1, which used the KO mouthrinse, and Group 2, which used a placebo. The participants used their assigned mouthrinses for three months. The success of each participant was measured using the mean cold air stimulus response (VAS) and Schiff sensitivity score.
Results: A significant decrease (p=0.00) in hypersensitivity in patients treated with potassium oxalate mouthrinse was observed.
Conclusion: Mouthrinse containing 1.4% potassium oxalate consistently demonstrated effectiveness in reducing dentinal hypersensitivity after three months of use.
Article Details
This work is licensed under a Creative Commons Attribution 4.0 International License.
This work is licensed under a Creative Commons Attribution 4.0 International License.
References
- Sharma D, McGuire JA, Gallob JT, Amini P. Randomised clinical efficacy trial of potassium oxalate mouthrinse in relieving dentinal sensitivity. J Dent. 2013;41 Suppl 4:S40-8. https://doi.org/10.1016/S0300-5712(13)70005-8
- Lynch MC, Perfekt R, McGuire JA, Milleman J, Gallob J, Amini P, Milleman K. Potassium oxalate mouthrinse reduces dentinal hypersensitivity: A randomized controlled clinical study. J Am Dent Assoc. 2018;149(7):608-618. https://doi.org/10.1016/j.adaj.2018.02.027
- Burnett GR, Gallob JT, Milleman KR, Mason S, Patil A, Budhawant C, Milleman JL. Potassium oxalate oral rinses for long-term relief from dentinal hypersensitivity: Three randomised controlled studies. J Dent. 2018;70:23-30. https://doi.org/10.1016/j.jdent.2017.12.004
- Pashley DH, Livingston MJ, Reeder OW, Horner J. Effects of the degree of tubule occlusion on the permeability of human dentine, in vitro. Arch Oral Biol. 1978; 23: 1127-33. https://doi.org/10.1016/0003-9969(78)90119-X
- Molina A, García-Gargallo A, Montero E, et al. Clinical efficacy of desensitizing mouthwashes for the control of dentin hypersensitivity and root sensitivity: a systematic review and meta-analysis. Int J Dent Hyg. 2017;15:84–94. https://doi.org/10.1111/idh.12250
- Sharma D, Hong CX, Heipp PS. A novel potassium oxalate-containing tooth-desensitising mouthrinse: A comparative in vitro study. J Dent. 2013;41:18-S27. https://doi.org/10.1016/S0300-5712(13)70003-4
- Gillam DG, Khan N, Mordan NJ, Barber PM. Scanning electron microscopy (SEM) investigation of selected desensitizing agents in the dentine disc model. Endod Dent Traumatol. 1999;15:198-204. https://doi.org/10.1111/j.1600-9657.1999.tb00774.x
- Gillam DG, Mordan NJ, Sinodinou AD, Tang JY, Knowles JC, Gibson IR. The effects of oxalate-containing products on the exposed dentine surface: an SEM investigation. J Oral Rehabil. 2001;28:1037-1044. https://doi.org/10.1046/j.1365-2842.2001.00775.x
- Hall C, Sufi F, Milleman JL, et al. Efficacy of a 3% potassium nitrate mouthrinse for the relief of dentinal hypersensitivity: An 8-week randomized controlled study. J Am Dent Assoc. 2019;150:204–212. https://doi.org/10.1016/j.adaj.2018.10.023
- Osmari D, Fraga S, de Oliveira Ferreira AC. In-office treatments for dentin hypersensitivity: a randomized split-mouth clinical trial. Oral Health Prev Dent. 2018;16:125–130.
- Manohar B, Pebbili KK, Shukla K. Potassium oxalate-based mouthrinse for rapid relief in dentinal hypersensitivity. J Oral Res Rev. 2024;16(1):72-79. https://doi.org/10.4103/jorr.jorr_40_23
- Schiff T, Dotson M, Cohen S, DeVizio W, Volpe A. Efficacy of a dentifrice containing potassium nitrate, soluble pyrophosphate, PVM/MA copolymer, and sodium fluoride on dentinal hypersensitivity: A twelve week clinical study. J Clin Dent 1994;5 (Sp Is):87-92.
- Huskisson EC. Measurement of pain. Lancet. 1974;304(7889):1127-1131. https://doi.org/10.1016/S0140-6736(74)90884-8
- Hodosh N, A superior desensitizer-Potassium nitrate. J Am Dent Assoc.1974; 88 (4): 831-832. https://doi.org/10.14219/jada.archive.1974.0174
- Orchardson R, Gillam DG. The efficacy of potassium salts as agents for treating dentin hypersensitivity. J Orofac Pain. 2000;14:9–19.