Section Original Articles

An in vitro study to evaluate and compare the remineralizing potential among Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) with fluoride and surface pre-reacted glass (S-PRG) fillers using quantitative analysis.

Comparison between two types of remineralizing agents.
Shabista Jabi
Swati Diwedi
Vinod Upadhyay
Ahsan Abdullah
Mohammad Sarfaraj
Ankur Mishra

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Abstract

Background- Early treatment of white spot lesions is essential to prevent the progression of the lesion.


Aim - To evaluate and compare the remineralizing potential of CPP-ACP with fluoride (Casein Phospho Peptide-Amorphous Calcium Phosphate) and S-PRG fillers (Surface Pre reacted glass fillers) using atomic absorption spectroscopy and colorimetric method.


Materials and methods- Forty sound human premolars were used in this study. They were divided into two groups (A & B), consisting of 20 samples in each. White spot lesions (WSLs) were established on the window (4x4 mm2) created on the buccal surfaces of the samples. Samples in group A were treated with casein phosphopeptide amorphous calcium phosphate (CPP-ACP) with fluoride, those of group B were treated with S-PRG Fillers. The sample teeth were immersed in a demineralizing solution for 4 days. All the samples were subjected to loss of mineral content (wt %), i.e., calcium, using atomic absorption spectroscopy and phosphorus using the colorimetric method.


Results- Statistical analysis was performed using one?way analysis of variance, Tukey’s and paired t?tests. Group A exhibited the highest remineralizing potential, followed by Group B. Statistically, a significant difference (p=0.001) was observed between the two groups. 


Conclusion- There was a significant difference in remineralizing potential of CPP-ACP with fluoride and S-PRG Fillers. CPP-ACP with fluoride appears to be an effective technique in the remineralization of white spot lesions.

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Author Biographies

Shabista Jabi, Career Postgraduate Institute of Dental Sciences & Hospital

Postgraduate Student, Department of Paediatric and Preventive Dentistry, Career Postgraduate Institute of Dental Sciences & Hospital, Lucknow, India.

Swati Diwedi, Career Postgraduate Institute of Dental Sciences & Hospital

Professor, Department of Paediatric and Preventive Dentistry, Department of Paediatric and Preventive Dentistry, Career Postgraduate Institute of Dental Sciences & Hospital, Lucknow, India.

Vinod Upadhyay, Career Postgraduate Institute of Dental Sciences & Hospital

Professor, Department of Paediatric and Preventive Dentistry, Department of Paediatric and Preventive Dentistry, Career Postgraduate Institute of Dental Sciences & Hospital, Lucknow, India.

 

Ahsan Abdullah, Career Postgraduate Institute of Dental Sciences & Hospital

Reader, Department of Paediatric and Preventive Dentistry, Department of Paediatric and Preventive Dentistry, Career Postgraduate Institute of Dental Sciences & Hospital, Lucknow, India.

Mohammad Sarfaraj, Career Postgraduate Institute of Dental Sciences & Hospital

Senior Lecturer, Department of Paediatric and Preventive Dentistry, Department of Paediatric and Preventive Dentistry, Career Postgraduate Institute of Dental Sciences & Hospital, Lucknow, India.

Ankur Mishra, Career Postgraduate Institute of Dental Sciences & Hospital

Senior Lecturer, Department of Paediatric and Preventive Dentistry, Department of Paediatric and Preventive Dentistry, Career Postgraduate Institute of Dental Sciences & Hospital, Lucknow, India.

CITATION
DOI: 10.37983/IJDM.2021.3301
Published: 2021-08-01
How to Cite
Jabi, S., Diwedi, S., Upadhyay, V., Abdullah, A., Sarfaraj, M. ., & Mishra, A. (2021). An in vitro study to evaluate and compare the remineralizing potential among Casein Phosphopeptide-amorphous Calcium Phosphate (CPP-ACP) with fluoride and surface pre-reacted glass (S-PRG) fillers using quantitative analysis.: Comparison between two types of remineralizing agents. International Journal of Dental Materials, 3(3), 70-75. https://doi.org/10.37983/IJDM.2021.3301

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