Comparative Evaluation of Fluoride Release from Glass Ionomer Cement Modified with Different Concentrations of Chitosan: An in vitro Study


Article Sidebar

PDF 71
Published: Jul 31, 2024
DOI: https://doi.org/10.37983/IJDM.2024.6202
Keywords:
Chitosan, Electrodes, Fluoride release, GIC
Section
Original Articles
Statistic

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Main Article Content

Bharath Makonahalli Jaganath
Sri Hasanamba Dental College and Hospital
Sahadev Chickmagarvalli Krishnegowda
Sri Hasanamba Dental College and Hospital
Sandeep Rudranaik
Sri Hasanamba Dental College and Hospital
Prashanth Sharma Ajakkala
Sri Hasanamba Dental College and Hospital
https://orcid.org/0009-0001-8572-482X

Abstract

Background: Restorative materials releasing fluoride are essential for caries prevention. Among the restoratives, glass ionomer cement (GIC) has a remarkable fluoride-releasing ability.


Aim: To evaluate and compare the effect of three different concentrations of Chitosan-modified GIC on its fluoride-releasing properties.


Materials and methods: Thirty-two disk-shaped pellets having dimensions of 10 x 2 mm were made with Restorative GIC (RX Ease, Shofu, Japan) using silicone molds. Specimens were divided into four groups based on the chitosan concentration in GIC liquid, with eight (n=8) in each. Group 1: Control (Unmodified), Group 2: 10 % Chitosan, Group 3: 20 % Chitosan, and Group 4: 30 % Chitosan. The specimens of each group were immersed in deionized water at various time intervals. Electrodes selective for fluoride ions were employed to analyze the amount of fluoride release at 1, 7, and 14 days. Analysis of variance (ANOVA) followed by Post hoc Tukey’s tests were performed for statistical analysis of the obtained data. Significance levels were set at p less than 0.05.


Results: Unmodified GICs exhibited higher fluoride release compared to chitosan-modified GICs at all time points. All samples initially released a high amount of fluoride, which decreased over time.


Conclusion: The addition of chitosan to GIC decreased its fluoride-releasing ability. Unmodified GIC showed better fluoride release than chitosan-modified GICs.

Article Details


How to Cite
Jaganath, B. M., Krishnegowda, S. C., Rudranaik, S., & Ajakkala, P. S. (2024). Comparative Evaluation of Fluoride Release from Glass Ionomer Cement Modified with Different Concentrations of Chitosan: An in vitro Study. International Journal of Dental Materials, 6(2), 37–40. https://doi.org/10.37983/IJDM.2024.6202
Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

This work is licensed under a Creative Commons Attribution 4.0 International License.

Author Biographies

Bharath Makonahalli Jaganath, Sri Hasanamba Dental College and Hospital

Professor, Department of Conservative and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India.

Sahadev Chickmagarvalli Krishnegowda, Sri Hasanamba Dental College and Hospital

Professor and Head, Department of Conservative and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India.

Sandeep Rudranaik, Sri Hasanamba Dental College and Hospital

Professor, Department of Conservative and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India.

Prashanth Sharma Ajakkala, Sri Hasanamba Dental College and Hospital

Postgraduate Student, Department of Conservative and Endodontics, Sri Hasanamba Dental College and Hospital, Hassan, Karnataka, India.

References

  1. Pitts NB, Twetman S, Fisher J, Marsh PD. Understanding dental caries as a non-communicable disease. Br Dent J. 2021;231(12):749–53. https://doi.org/10.1038/s41415-021-3775-4
  2. Pizzo G, Piscopo MR, Pizzo I, Giuliana G. Community water fluoridation and caries prevention: a critical review. Clin Oral Investig. 2007;11(3):189–93. https://doi.org/10.1007/s00784-007-0111-6
  3. Hicks J, Garcia-Godoy F, Donly K, Flaitz C. Fluoride-releasing restorative materials and secondary caries. J Calif Dent Assoc. 2003;31(3):229–45. https://doi.org/10.1080/19424396.2003.12224158
  4. Culbertson BM. Glass-ionomer dental restoratives. Prog Polym Sci. 2001;26(4):577–604. https://doi.org/10.1016/S0079-6700(01)00006-5
  5. Petri DFS, Donega J, Benassi AM, Bocangel JAJS. Preliminary study on chitosan modified glass ionomer restoratives. Dent Mater. 2007;23(8):1004–10. https://doi.org/10.1016/j.dental.2006.06.038
  6. Rinaudo M. Chitin and chitosan: properties and applications. Prog Polym Sci 2006;31(7):603–32. https://doi.org/10.1016/j.progpolymsci.2006.06.001
  7. Lehr CM, Bouwstra JA, Schacht EH, Junginger HE. In vitro evaluation of mucoadhesive properties of chitosan and some other natural polymers. Int J Pharmacy. 1992;78(1-3): 43–48. https://doi.org/10.1016/0378-5173(92)90353-4
  8. Martínez JP, Falomir MP, Gozalbo D. Chitin: a structural biopolysaccharide with multiple applications. eLS. 2014;1-10. https://doi.org/10.1002/9780470015902.a0000694.pub3
  9. Mohire NC, Yadav AV. Chitosan-based polyherbal toothpaste: As novel oral hygiene product. Ind J Dent Res. 2010;21(3):380. https://doi.org/10.4103/0970-9290.70808
  10. Petri DFS, Donega J, Benassi AM, Bocangel JAJS. Preliminary study on chitosan modified glass ionomer restoratives. Dent Mater. 2007;23(8):1004–10. https://doi.org/10.1016/j.dental.2006.06.038
  11. Karthick A, Kavitha M, Loganathan SC, Malarvizhi D. Evaluation of microshear bond strength of chitosan modified GIC. World J Med Sci. 2014;10(2):169–73. https://doi.org/10.5829/idosi.wjms.2014.10.2.82184
  12. Sidhu SK, editor. Glass-ionomers in dentistry. Springer; 2015. https://doi.org/10.1007/978-3-319-22626-2
  13. Mousavinasab SM, Meyers I. Fluoride release by glass ionomer cements, compomer and giomer. Dent Res J. 2009;6(2):75.
  14. Al Ibrahim NS, Tahmassebi JF, Toumba KJ. In vitro and in vivo assessment of newly developed slow-release fluoride glass device. Eur Arch Paediatr Dent Off J Eur Acad Paediatr Dent. 2010;11(3):131–5. https://doi.org/10.1007/BF03262728
  15. Harhash AY, Elsayad I, Zaghloul AG. A comparative in vitro study on fluoride release and water sorption of different flowable esthetic restorative materials. Eur J Dent. 2017;11(2):174–179. https://doi.org/10.4103/ejd.ejd_228_16
  16. Tay FR, Pashley EL, Huang C, Hashimoto M, Sano H, Smales RJ et al. The glass-ionomer phase in resin-based restorative materials. J Dent Res. 2001;80(9):1808-12. https://doi.org/10.1177/00220345010800090701
  17. Hasan AM, Sidhu SK, Nicholson JW. Fluoride release and uptake in enhanced bioactivity glass ionomer cement (“glass carbomer™”) compared with conventional and resin-modified glass ionomer cements. J Appl Oral Sci. 2019;27:e20180230. https://doi.org/10.1590/1678-7757-2018-0230
  18. Pellizzari VA, Michels AC, Luiz ST, de Souza EM, Tabchoury C, Rached RN. Fluoride ion release of self-adhesive resin cements and their potential to inhibit in situ enamel and dentin demineralization. Oper Dent. 2017;42(5):548–58. https://doi.org/10.2341/16-115-L
  19. Nagi SM, Moharam LM, El Hoshy AZ. Fluoride release and recharge of enhanced resin modified glass ionomer at different time intervals. Futur Dent J. 2018;4(2):221–4. https://doi.org/10.1016/j.fdj.2018.06.005
  20. Nishanthine C, Miglani R, Indira R, Poorni S, Srinivasan MR, Robaian A et al. Evaluation of fluoride release in chitosan-modified glass ionomer cements. Int Dent J. 2022;72(6):785-91. https://doi.org/10.1016/j.identj.2022.05.005
  21. Wiegand A, Buchalla W, Attin T. Review on fluoride-releasing restorative materials—fluoride release and uptake characteristics, antibacterial activity and influence on caries formation. Dent Mater. 2007;23(3):343-62. https://doi.org/10.1016/j.dental.2006.01.022
  22. Miranda LA, Weidlich P, Samuel SMW, Maltz M. Fluoride release from restorative materials coated with an adhesive. Braz Dent J. 2002;13(1):39–43.
  23. Martinez-Mier EA, Cury JA, Heilman JR, Katz BP, Levy SM, Li Y et al. Development of gold standard ion-selective electrode-based methods for fluoride analysis. Caries Res. 2011;45(1):3-12. https://doi.org/10.1159/000321657